Endocrine disruptors and male reproductive function - a short review
نویسندگان
چکیده
منابع مشابه
Endocrine disruptors and estrogenic effects on male reproductive axis.
Endocrine disruptors (e.g., polychlorinated biphenyls [PCBs], dichlorodiphenyl-trichloroethane [DDT], dioxin, and some pesticides) are estrogen-like and anti-androgenic chemicals in the environment. They mimic natural hormones, inhibit the action of hormones, or alter the normal regulatory function of the endocrine system and have potential hazardous effects on male reproductive axis causing in...
متن کاملEndocrine Disruptors and Leydig Cell Function
During the past decades, a large body of information concerning the effects of endocrine disrupting compounds (EDCs) on animals and humans has been accumulated. EDCs are of synthetic or natural origin and certain groups are known to disrupt the action of androgens and to impair the development of the male reproductive tract and external genitalia. The present overview describes the effects of t...
متن کامل[Impact of endocrine disruptors on the reproductive function and sexual response of men and women].
Os disruptores endócrinos são substâncias químicas naturais ou sintéticas, também contidas em compostos fungicidas, pesticidas e inseticidas, que apresentam ação antiandrogênica e estrogênica. Alguns desses compostos podem manter suas propriedades químicas na natureza por longos anos contaminando o ar, as águas e o solo, sendo acumuladas nas plantas, nos animais e no homem. Muitos são, potencia...
متن کاملEpigenetic transgenerational actions of endocrine disruptors and male fertility.
Transgenerational effects of environmental toxins require either a chromosomal or epigenetic alteration in the germ line. Transient exposure of a gestating female rat during the period of gonadal sex determination to the endocrine disruptors vinclozolin (an antiandrogenic compound) or methoxychlor (an estrogenic compound) induced an adult phenotype in the F1 generation of decreased spermatogeni...
متن کاملEndocrine disruptors, gene deregulation and male germ cell tumors.
Endocrine disruptors (EDs) belong to a large group of compounds, usually present as environmental pollutants, which can alter the homeostasis of living organisms by modifying hormonal balance and changing the normal patterns of gene regulation during development and cell differentiation. Hence, the development of male gonads and their functionality may be affected by exposure to specific EDs or...
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ژورنال
عنوان ژورنال: International Journal of Andrology
سال: 2000
ISSN: 0105-6263,1365-2605
DOI: 10.1046/j.1365-2605.2000.00015.x